Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4<sup>+</sup>CD8<sup>+</sup> thymocytes
<p>Abstract</p> <p>Background</p> <p>The outcome of untreated HIV-1 infection is progression to AIDS and death in nearly all cases. Some important exceptions are the small number of patients infected with HIV-1 deleted for the accessory gene, <it>nef</it>. W...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-05-01
|
| Series: | Retrovirology |
| Subjects: | |
| Online Access: | http://www.retrovirology.com/content/9/1/44 |