Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-a-induced epithelial-mesenchymal transition of MCF-7 cells

Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-a-induced epithelial-mesenchymal transition of MCF-7 cells

The microenvironment of the tumor plays an important role in facilitating cancer progression and activating dormant cancer cells. Most tumors are infiltrated with inflammatory cells which secrete cytokines such as tumor necrosis factor-a (TNF-a). To evaluate the role of TNF-a in the development of c...

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Bibliographic Details
Main Authors: R. Dong, Q. Wang, X.L. He, Y.K. Chu, J.G. Lu, Q.J. Ma
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Tumor necrosis factor-a
Nuclear factor kappa B
Reactive oxygen species
Snail
E-cadherin
Epithelial-mesenchymal transition
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800007

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800007

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