Flurbiprofen: A Study of the Behavior of the Scalemate by Chromatography, Sublimation, and NMR

Flurbiprofen: A Study of the Behavior of the Scalemate by Chromatography, Sublimation, and NMR

2-(2-Fluoro-4-biphenyl) propionic acid (flurbiprofen), from the phenylalkanoic acid family of nonsteroidal anti-inflammatory drugs (NSAID’s), is currently on the pharmaceutical market as a racemate. This racemic compound was tested for its propensity to undergo the self-disproportionation of enantio...

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Bibliographic Details
Main Authors: Magdalena Kwiatkowska, Alicja Wzorek, Anna Kolbus, Mariusz Urbaniak, Jianlin Han, Vadim A. Soloshonok, Karel D. Klika
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Symmetry
Subjects:
flurbiprofen
fluorine-containing pharmaceuticals
self-induced diastereomeric anisochronism (SIDA)
enantiomeric analysis
molecular association
NMR
Online Access:https://www.mdpi.com/2073-8994/13/4/543

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https://www.mdpi.com/2073-8994/13/4/543

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