Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis

Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis

Abstract The influence of the gut microbiota on traumatic brain injury (TBI) is presently unknown. This knowledge gap is of paramount clinical significance as TBI patients are highly susceptible to alterations in the gut microbiota by antibiotic exposure. Antibiotic-induced gut microbial dysbiosis e...

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Bibliographic Details
Main Authors: Marta Celorrio, Miguel A. Abellanas, James Rhodes, Victoria Goodwin, Jennie Moritz, Sangeetha Vadivelu, Leran Wang, Rachel Rodgers, Sophia Xiao, Ilakkia Anabayan, Camryn Payne, Alexandra M. Perry, Megan T. Baldridge, Maria S. Aymerich, Ashley Steed, Stuart H. Friess
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Acta Neuropathologica Communications
Subjects:
Traumatic brain injury
Gut microbial dysbiosis
Antibiotics
Fear conditioning
Microglia
Monocytes
Online Access:https://doi.org/10.1186/s40478-021-01137-2

Internet

https://doi.org/10.1186/s40478-021-01137-2

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