Adaptive Evolution of Human-Isolated H5Nx Avian Influenza A Viruses

Adaptive Evolution of Human-Isolated H5Nx Avian Influenza A Viruses

Avian influenza A viruses (AIVs) H5N1, first identified in 1996, are highly pathogenic in domestic poultry and continue to occasionally infect humans. In this study, we sought to identify genetic changes that occurred during their multiple invasions to humans. We evaluated all available H5Nx AIV gen...

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Bibliographic Details
Main Authors: Fucheng Guo, Yiliang Li, Shu Yu, Lu Liu, Tingting Luo, Zhiqing Pu, Dan Xiang, Xuejuan Shen, David M. Irwin, Ming Liao, Yongyi Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Microbiology
Subjects:
H5Nx
Avian influenza A virus
convergent evolution
human infection
host shift
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01328/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01328/full

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