CMPK1 Regulated by miR-130b Attenuates Response to 5-FU Treatment in Gastric Cancer

Gastric cancer (GC) remains a major world-wide challenge, especially in Asian countries. Chemotherapy with 5-fluorouracil (5-FU) and cisplatin is used as the first-line treatment and development of chemoresistance is a major cause of progression. UMP/CMP kinase is responsible for the phosphorylation...

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Bibliographic Details
Main Authors: Huaizhu Chu, Nahui Han, Jianguo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.637470/full