A high-fructose diet induces changes in pp185 phosphorylation in muscle and liver of rats

A high-fructose diet induces changes in pp185 phosphorylation in muscle and liver of rats

Insulin stimulates the tyrosine kinase activity of its receptor resulting in the tyrosine phosphorylation of pp185, which contains insulin receptor substrates IRS-1 and IRS-2. These early steps in insulin action are essential for the metabolic effects of insulin. Feeding animals a high-fructose diet...

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Bibliographic Details
Main Authors: M. Ueno, R.M.N. Bezerra, M.S. Silva, D.Q. Tavares, C.R. Carvalho, M.J.A. Saad
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2000-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
fructose
insulin receptor
pp185 phosphorylation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200004

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