Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.

We have been studying the action mechanisms of valproic acid (VPA) in fission yeast Schizosaccharomyces pombe by developing a genetic screen for mutants that show hypersensitivity to VPA. In the present study, we performed a genome-wide screen of 3004 haploid deletion strains and confirmed 148 delet...

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Bibliographic Details
Main Authors: Lili Zhang, Ning Ma, Qingbin Liu, Yan Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3702616?pdf=render