Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms

<p>Abstract</p> <p>Background</p> <p>The fidelity of DNA replication serves as the nidus for both genetic evolution and genomic instability fostering disease. Single nucleotide polymorphisms (SNPs) constitute greater than 80% of the genetic variation between individuals...

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Bibliographic Details
Main Authors: Arehart Eric, Gleim Scott, White Bill, Hwa John, Moore Jason H
Format: Article
Language:English
Published: BMC 2009-03-01
Series:BioData Mining
Online Access:http://www.biodatamining.org/content/2/1/2