Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis

Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis

Transient receptor potential vanilloid 1 (TRPV1) channels are involved in several inflammatory diseases. However, their action is still controversial, and both pro-inflammatory and anti-inflammatory roles have been described. We used a strain of TRPV1-KO mice to characterize the role of these channe...

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Bibliographic Details
Main Authors: Gabriele Musumeci, Giorgio Grasselli, Silvia Rossi, Valentina De Chiara, Alessandra Musella, Caterina Motta, Valeria Studer, Giorgio Bernardi, Nabila Haji, Helena Sepman, Diego Fresegna, Mauro Maccarrone, Georgia Mandolesi, Diego Centonze
Format: Article
Language:English
Published: Elsevier 2011-09-01
Series:Neurobiology of Disease
Subjects:
EAE
EPSCs
IPSCs
Multiple sclerosis
Neuroprotection
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001872

Internet

http://www.sciencedirect.com/science/article/pii/S0969996111001872

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