Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex.
Viral vectors injected into the mouse brain offer the possibility for localized genetic modifications in a highly controlled manner. Lentivector injection into mouse neocortex transduces cells within a diameter of approximately 200µm, which closely matches the lateral scale of a column in...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2007-11-01
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Series: | Frontiers in Integrative Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/neuro.07.001.2007/full |