Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial.

Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial.

Abdominal bloating is a common and bothersome symptom of chronic idiopathic constipation. The objective of this trial was to evaluate the efficacy and safety of linaclotide in patients with chronic idiopathic constipation and concomitant moderate-to-severe abdominal bloating.This Phase 3b, randomize...

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Bibliographic Details
Main Authors: Brian E Lacy, Ron Schey, Steven J Shiff, Bernard J Lavins, Susan M Fox, Xinwei D Jia, Rick E Blakesley, Xinming Hao, Jacquelyn A Cronin, Mark G Currie, Caroline B Kurtz, Jeffrey M Johnston, Anthony J Lembo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519259?pdf=render

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http://europepmc.org/articles/PMC4519259?pdf=render

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