Enhancing endosomal escape of transduced proteins by photochemical internalisation.

Induced internalisation of functional proteins into cultured cells has become an important aspect in a rising number of in vitro and in vivo assays. The endo-lysosomal entrapment of the transduced proteins remains the major problem in all transduction protocols. In this study we compared the efficie...

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Bibliographic Details
Main Authors: Kevin Mellert, Markus Lamla, Klaus Scheffzek, Rainer Wittig, Dieter Kaufmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528648?pdf=render