Telmisartan and Rosuvastatin Synergistically Ameliorate Dementia and Cognitive Impairment in Older Hypertensive Patients With Apolipoprotein E Genotype

Telmisartan and Rosuvastatin Synergistically Ameliorate Dementia and Cognitive Impairment in Older Hypertensive Patients With Apolipoprotein E Genotype

Objective: To investigate the effect of telmisartan, rosuvastatin, or their combination on dementia and to understand the impact of apolipoprotein E (APOE) genotype on the effect of the medications in older patients with hypertension.Methods: This is a double-blind, randomized, and placebo-controlle...

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Bibliographic Details
Main Authors: Wenjing Hu, Ying Li, Yingxin Zhao, Yuanli Dong, Yi Cui, Shangwen Sun, Gary Gong, Hua Zhang, Qiang Chai, Juan Wang, Zhendong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
dementia
cognitive impairment
apolipoprotein E
lipid lowering
anti-hypertension
hypertension
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00154/full

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https://www.frontiersin.org/article/10.3389/fnagi.2020.00154/full

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