Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells

Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells

Abstract Background Allogeneic cardiac-derived progenitor cells (CPC) without immunosuppression could provide an effective ancillary therapy to improve cardiac function in reperfused myocardial infarction. We set out to perform a comprehensive preclinical feasibility and safety evaluation of porcine...

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Bibliographic Details
Main Authors: Veronica Crisostomo, Claudia Baez, José Luis Abad, Belén Sanchez, Virginia Alvarez, Rosalba Rosado, Guadalupe Gómez-Mauricio, Olivier Gheysens, Virginia Blanco-Blazquez, Rebeca Blazquez, José Luis Torán, Javier G. Casado, Susana Aguilar, Stefan Janssens, Francisco M. Sánchez-Margallo, Luis Rodriguez-Borlado, Antonio Bernad, Itziar Palacios
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Stem Cell Research & Therapy
Subjects:
Cardiac progenitor/stem cells
CPC
Acute myocardial infarction
Swine model
Allogeneic
Intracoronary administration
Online Access:http://link.springer.com/article/10.1186/s13287-019-1237-6

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http://link.springer.com/article/10.1186/s13287-019-1237-6

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