Atomistic Insight into the Role of Threonine 127 in the Functional Mechanism of Channelrhodopsin-2

Atomistic Insight into the Role of Threonine 127 in the Functional Mechanism of Channelrhodopsin-2

Channelrhodopsins (ChRs) belong to the unique class of light-gated ion channels. The structure of channelrhodopsin-2 from <i>Chlamydomonas reinhardtii</i> (<i>Cr</i>ChR2) has been resolved, but the mechanistic link between light-induced isomerization of the chromophore retina...

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Bibliographic Details
Main Authors: David Ehrenberg, Nils Krause, Mattia Saita, Christian Bamann, Rajiv K. Kar, Kirsten Hoffmann, Dorothea Heinrich, Igor Schapiro, Joachim Heberle, Ramona Schlesinger
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Applied Sciences
Subjects:
channelrhodopsin
resonance raman
flash photolysis
hybrid qm/mm simulation
electrophysiology
Online Access:https://www.mdpi.com/2076-3417/9/22/4905

Internet

https://www.mdpi.com/2076-3417/9/22/4905

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