Molecular and Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System: Implications for Pathology

Molecular and Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System: Implications for Pathology

Under aerobic conditions, mitochondrial oxidative phosphorylation (OXPHOS) converts the energy released by nutrient oxidation into ATP, the currency of living organisms. The whole biochemical machinery is hosted by the inner mitochondrial membrane (mtIM) where the protonmotive force built by respira...

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Bibliographic Details
Main Authors: Salvatore Nesci, Fabiana Trombetti, Alessandra Pagliarani, Vittoria Ventrella, Cristina Algieri, Gaia Tioli, Giorgio Lenaz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Life
Subjects:
oxidative phosphorylation
respiratory supercomplexes
ROS
ATP synthase/hydrolase
mitochondrial dysfunction
mitochondrial permeability transition pore
Online Access:https://www.mdpi.com/2075-1729/11/3/242

Internet

https://www.mdpi.com/2075-1729/11/3/242

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