Roles of gap junctions, connexins and pannexins in epilepsy

Roles of gap junctions, connexins and pannexins in epilepsy

Enhanced gap junctional communication (GJC) between neurons is considered a major factor underlying the neuronal synchrony driving seizure activity. In addition, the hippocampal sharp wave ripple complexes, associated with learning and seizures, are diminished by GJC blocking agents. Although gap ju...

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Bibliographic Details
Main Authors: Shanthini eMylvaganam, Meera eRamani, Michal eKrawczyk, Peter L Carlen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Physiology
Subjects:
Connexins
Epilepsy
Gap Junctions
Neurons
Animal Models
glia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00172/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00172/full

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