Retrovirus insertion site analysis of LGL leukemia patient genomes

Retrovirus insertion site analysis of LGL leukemia patient genomes

Abstract Background Large granular lymphocyte (LGL) leukemia is an uncommon cancer characterized by sustained clonal proliferation of LGL cells. Antibodies reactive to retroviruses have been documented in the serum of patients with LGL leukemia. Culture or molecular approaches have to date not been...

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Bibliographic Details
Main Authors: Weiling Li, Lei Yang, Robert S. Harris, Lin Lin, Thomas L. Olson, Cait E. Hamele, David J. Feith, Thomas P. Loughran, Mary Poss
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Genomics
Subjects:
Large granular lymphocyte leukemia
Retrovirus
HERV-K
Genomic insertion
Visualization tool
Online Access:http://link.springer.com/article/10.1186/s12920-019-0549-9

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http://link.springer.com/article/10.1186/s12920-019-0549-9

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