Xiaoyaosan Exerts Antidepressant Effect by Downregulating RAGE Expression in Cingulate Gyrus of Depressive-Like Mice

Xiaoyaosan Exerts Antidepressant Effect by Downregulating RAGE Expression in Cingulate Gyrus of Depressive-Like Mice

Xiaoyaosan (XYS), as a classic Chinese medicine compound, has been proven to have antidepressant effect in many studies, but its mechanism has not been clarified. In our previous studies, we found that chronic stress can induce depressive-like behavior and lead to emotion-related cingulate gyrus (Cg...

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Bibliographic Details
Main Authors: Weixin Yan, Zhaoyang Dong, Di Zhao, Jun Li, Ting Zeng, Chan Mo, Lei Gao, Zhiping Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
chronic stress
xiaoyaosan
functional connectivity
cingulate gyrus
receptor of advanced glycation protein end product
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.703965/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.703965/full

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