Combined treatment of sorafenib and doxorubicin-loaded microbubble-albumin nanoparticle complex for hepatocellular carcinoma: A feasibility study.

<h4>Purpose</h4>To assess the feasibility of the combined sorafenib (SOR) and doxorubicin-loaded microbubble-albumin nanoparticle complex (DOX-MAC) treatment effect in an orthotopic rat model of hepatocellular carcinoma (HCC).<h4>Materials and methods</h4>Sixty-two rats with...

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Bibliographic Details
Main Authors: Seunghyun Lee, Jung Hoon Kim, Hyungwon Moon, Hak Jong Lee, Joon Koo Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243815