Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70
<p>Abstract</p> <p>Background</p> <p>For optimal T cell activation it is desirable that dendritic cells (DCs) display peptides within MHC molecules as signal 1, costimulatory molecules as signal 2 and, in addition, produce IL-12p70 as signal 3. IL-12p70 polarizes T cell...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-04-01
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| Series: | Journal of Translational Medicine |
| Online Access: | http://www.translational-medicine.com/content/5/1/18 |