Gene expression profiles resulting from stable loss of p53 mirrors its role in tissue differentiation.

The tumor suppressor gene p53 is involved in a variety of cellular activities such as cellular stress responses, cell cycle regulation and differentiation. In our previous studies we have shown p53's transcription activating role to be important in osteoblast differentiation. There is still a d...

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Bibliographic Details
Main Authors: Oliver Couture, Eric Lombardi, Kendra Davis, Emily Hays, Nalini Chandar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842970?pdf=render