XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling

<p>Abstract</p> <p>Background</p> <p>X-linked inhibitor of apoptosis protein (XIAP) is often overexpressed in cancer cells, where it plays a key role in survival and also promotes invasiveness. To date however, the extracellular signals and intracellular pathways regula...

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Bibliographic Details
Main Authors: Van Themsche Céline, Chaudhry Parvesh, Leblanc Valérie, Parent Sophie, Asselin Eric
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/216