Mechanisms of enhancer action: the known and the unknown

Abstract Differential gene expression mechanisms ensure cellular differentiation and plasticity to shape ontogenetic and phylogenetic diversity of cell types. A key regulator of differential gene expression programs are the enhancers, the gene-distal cis-regulatory sequences that govern spatiotempor...

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Bibliographic Details
Main Authors: Anil Panigrahi, Bert W. O’Malley
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02322-1