Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells

Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells

Abstract Background Appropriately modulating inflammation after traumatic brain injury (TBI) may prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of inflammation, including macrophages and microglia, possess a range of phenotypes relevant for an immunomod...

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Bibliographic Details
Main Authors: Syed Faaiz Enam, Sajidur Rahman Kader, Nicholas Bodkin, Johnathan G. Lyon, Mark Calhoun, Cesar Azrak, Pooja Munnilal Tiwari, Daryll Vanover, Haichen Wang, Philip J. Santangelo, Ravi Venkat Bellamkonda
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Neuroinflammation
Subjects:
Interleukin-4
IL-4
mRNA
Stem cell
MSC
Macrophage
Online Access:http://link.springer.com/article/10.1186/s12974-020-01860-y

Internet

http://link.springer.com/article/10.1186/s12974-020-01860-y

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