Decrease in formalin-inactivated respiratory syncytial virus (FI-RSV) enhanced disease with RSV G glycoprotein peptide immunization in BALB/c mice.

Respiratory syncytial virus (RSV) is a high priority target for vaccine development. One concern in RSV vaccine development is that a non-live virus vaccine would predispose for enhanced disease similar to that seen with the formalin inactivated RSV (FI-RSV) vaccine. Since a mAb specific to RSV G pr...

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Bibliographic Details
Main Authors: Gertrud U Rey, Congrong Miao, Hayat Caidi, Suvang U Trivedi, Jennifer L Harcourt, Ralph A Tripp, Larry J Anderson, Lia M Haynes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871585?pdf=render