Modeling atrial fibrosis in vitro—Generation and characterization of a novel human atrial fibroblast cell line

Modeling atrial fibrosis in vitro—Generation and characterization of a novel human atrial fibroblast cell line

Atrial fibrillation (AF) is regularly accompanied by cardiac fibrosis and concomitant heart failure. Due to the heterogeneous nature and complexity of fibrosis, the knowledge about the underlying mechanisms is limited, which prevents effective pharmacotherapy. A deeper understanding of cardiac fibro...

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Bibliographic Details
Main Authors: Stephan R. Künzel, Johanna S. E. Rausch, Charlotte Schäffer, Maximilian Hoffmann, Karolina Künzel, Erik Klapproth, Theresa Kant, Natalie Herzog, Jan‐Heiner Küpper, Kristina Lorenz, Svenja Dudek, Ramona Emig, Ursula Ravens, Eva A. Rog‐Zielinska, Rémi Peyronnet, Ali El‐Armouche
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:FEBS Open Bio
Subjects:
cardiovascular disease
cell culture
cell lines
fibroblasts
fibrosis
heart
Online Access:https://doi.org/10.1002/2211-5463.12896

Internet

https://doi.org/10.1002/2211-5463.12896

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