Folate-conjugated hydrophobicity modified glycol chitosan nanoparticles for targeted delivery of methotrexate in rheumatoid arthritis

Background: Targeted delivery to the Rheumatoid arthritis (RA) which is characterized by destruction and degeneration of bones due to chronic inflammation is of great need. RA being a chronic autoimmune disorder might result in severe disability and morbidity. A targeted delivery system is designed...

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Bibliographic Details
Main Authors: Zhongqing Wu, Kanna Xu, Jikang Min, Minchang Chen, Liping Shen, Jianxue Xu, Qi Jiang, Guohong Han, Le Pan, Haidong Li
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Journal of Applied Biomaterials & Functional Materials
Online Access:https://doi.org/10.1177/2280800020962629