Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and <it>HMGCR </it>splicing in disease risk

<p>Abstract</p> <p>Background</p> <p>Recent genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNP)s that are essentially unequivocally associated with peripheral cholesterol. Since the alleles of the <it>APOE </it>gene,...

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Bibliographic Details
Main Authors: Younkin Steven G, Zou Fanggeng, Simmons Christopher R, Estus Steven
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Molecular Neurodegeneration
Subjects:
SNP
Online Access:http://www.molecularneurodegeneration.com/content/6/1/62