Gene Expression Meta‐Analysis Reveals Concordance in Gene Activation, Pathway, and Cell‐Type Enrichment in Dermatomyositis Target Tissues

Objective We conducted a comprehensive gene expression meta‐analysis in dermatomyositis (DM) muscle and skin tissues to identify shared disease‐relevant genes and pathways across tissues. Methods Six publicly available data sets from DM muscle and two from skin were identified. Meta‐analysis was per...

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Bibliographic Details
Main Authors: Jessica Neely, Dmitry Rychkov, Manish Paranjpe, Michael Waterfield, Susan Kim, Marina Sirota
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.11081