Predictors of Response to Autologous Dendritic Cell Therapy in Glioblastoma Multiforme

Predictors of Response to Autologous Dendritic Cell Therapy in Glioblastoma Multiforme

BackgroundGlioblastoma (GBM) is the most common and lethal primary malignant glioma in adults. Dendritic cell (DC) vaccines have demonstrated promising results in GBM clinical trials. However, some patients do not respond well to DC therapy, with survival rates similar to those of conventional thera...

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Bibliographic Details
Main Authors: Chia-Ing Jan, Wan-Chen Tsai, Horng-Jyh Harn, Woei-Cherng Shyu, Ming-Chao Liu, Hsin-Man Lu, Shao-Chih Chiu, Der-Yang Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
autologous dendritic cell/tumor antigen
glioblastoma multiforme
tumor-infiltrating lymphocytes
immune checkpoints
peripheral blood mononuclear cell
programmed death protein 1 (PD-1+)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.00727/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.00727/full

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