Advanced glycation endproducts link inflammatory cues to upregulation of galectin-1 in diabetic retinopathy
Abstract Diabetic retinopathy (DR) is an inflammatory and progressive vaso-occlusive disease resulting in angiogenesis. Galectin-1 is a hypoxia-induced angiogenic factor associated with cancer and proliferative DR. Here we reveal a significant upregulation of galectin-1 in eyes of DR patients along...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-16499-8 |