Lycopene Exerts Neuroprotective Effects After Hypoxic–Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway

Lycopene Exerts Neuroprotective Effects After Hypoxic–Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway

Neonatal hypoxic-ischemic encephalopathy (HIE) is a brain injury caused by perinatal asphyxia and is the main cause of neonatal death and chronic neurological diseases. Protection of neuron after hypoxic-ischemic (HI) brain injury is considered as a potential therapeutic target of HI brain injury. T...

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Bibliographic Details
Main Authors: Changchang Fu, Yihui Zheng, Jinjin Zhu, Binwen Chen, Wei Lin, Kun Lin, Jianghu Zhu, Shangqin Chen, Peijun Li, Xiaoqin Fu, Zhenlang Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
poptosis
neuroprotection
lycopene
hypoxic-ischemic brain injury
Nrf2/NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.585898/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.585898/full

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