Two major gate-keepers in the self-renewal of neural stem cells: Erk1/2 and PLCγ1 in FGFR signaling

<p>Abstract</p> <p>Neural stem cells are undifferentiated precursor cells that proliferate, self-renew, and give rise to neuronal and glial lineages. Understanding the molecular mechanisms underlying their self-renewal is an important aspect in neural stem cell biology. The regulat...

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Bibliographic Details
Main Authors: Lee Jin-A, Jang Deok-Jin, Kaang Bong-Kiun
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/2/1/15