Increased concentrations of glutamate and glutamine in normal-appearing white matter of patients with multiple sclerosis and normal MR imaging brain scans.

In Multiple Sclerosis (MS) the relationship between disease process in normal-appearing white matter (NAWM) and the development of white matter lesions is not well understood. In this study we used single voxel proton 'Quantitative Magnetic Resonance Spectroscopy' (qMRS) to characterize th...

Full description

Bibliographic Details
Main Authors: Anders Tisell, Olof Dahlqvist Leinhard, Jan Bertus Marcel Warntjes, Anne Aalto, Örjan Smedby, Anne-Marie Landtblom, Peter Lundberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3629257?pdf=render