Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine

Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine

Abstract Background The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes. Although hESCs can indefinitely proliferate in culture, unlike transformed cancer cells, they are endowed with a cell...

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Bibliographic Details
Main Authors: Guillermo A. Videla-Richardson, Verónica A. Furmento, Carolina P. Garcia, Olivia Morris-Hanon, Gustavo E. Sevlever, Leonardo Romorini, María E. Scassa
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Molecular and Cell Biology
Subjects:
Human embryonic stem cells
Roscovitine
Cyclin-dependent kinases
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12860-019-0222-3

Internet

http://link.springer.com/article/10.1186/s12860-019-0222-3

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