RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells

RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells

Previously, we demonstrated that growth arrest-specific protein 6 (Gas6)/Axl or Mer signaling inhibited the transforming growth factor (TGF)-β1-induced epithelial−mesenchymal transition (EMT) in lung epithelial cells. Hepatocyte growth factor (HGF) has also been shown to inhibit T...

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Bibliographic Details
Main Authors: Jihye Jung, Kyungwon Yang, Hee-Ja Kim, Ye-Ji Lee, Minsuk Kim, Youn-Hee Choi, Jihee Lee Kang
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biomolecules
Subjects:
growth arrest-specific protein 6
hepatocyte growth factor
c-met
epithelial-mesenchymal transition
lung epithelial cells
Online Access:https://www.mdpi.com/2218-273X/9/10/565

Internet

https://www.mdpi.com/2218-273X/9/10/565

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