Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis.

<h4>Rationale</h4>Tuberculosis remains a worldwide problem, particularly with the advent of multi-drug resistance. Shortening therapy duration for Mycobacterium tuberculosis is a major goal, requiring generation of optimal kill rate and resistance-suppression. Combination therapy is requ...

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Bibliographic Details
Main Authors: George L Drusano, Michael Neely, Michael Van Guilder, Alan Schumitzky, David Brown, Steven Fikes, Charles Peloquin, Arnold Louie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25003557/pdf/?tool=EBI