The DNA hypermethylation phenotype of colorectal cancer liver metastases resembles that of the primary colorectal cancers

The DNA hypermethylation phenotype of colorectal cancer liver metastases resembles that of the primary colorectal cancers

Abstract Background Identifying molecular differences between primary and metastatic colorectal cancers—now possible with the aid of omics technologies—can improve our understanding of the biological mechanisms of cancer progression and facilitate the discovery of novel treatments for late-stage can...

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Bibliographic Details
Main Authors: Stephany Orjuela, Mirco Menigatti, Peter Schraml, Patryk Kambakamba, Mark D. Robinson, Giancarlo Marra
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
Normal colorectal mucosa
Colorectal cancer
Liver metastasis
DNA methylation
CpG sites
CpG islands
Online Access:http://link.springer.com/article/10.1186/s12885-020-06777-6

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http://link.springer.com/article/10.1186/s12885-020-06777-6

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