Quantitative proteomics and transcriptomics reveals metabolic differences in attracting and non-attracting human-in-mouse glioma stem cell xenografts and stromal cells

Quantitative proteomics and transcriptomics reveals metabolic differences in attracting and non-attracting human-in-mouse glioma stem cell xenografts and stromal cells

Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) show promise as cell-based delivery vehicles for anti-glioma therapeutics, due to innate tropism for gliomas. However, in clinically relevant human-in-mouse glioma stem cell xenograft models, BM-hMSCs tropism is variable. We compared the pr...

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Bibliographic Details
Main Authors:	Norelle C. Wildburger, Cheryl F. Lichti, Richard D. LeDuc, Mary Schmidt, Roger A. Kroes, Joseph R. Moskal, Carol L. Nilsson
Format:	Article
Language:	English
Published:	Elsevier 2015-09-01
Series:	EuPA Open Proteomics
Subjects:	Glioblastoma Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) Mass spectrometry Cancer proteomics Transcriptomics Fatty acid metabolism Glycolysis Pentose phosphate pathway ROS Glycosylation
Online Access:	http://www.sciencedirect.com/science/article/pii/S221296851530009X

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