The Preparation of New Phosphorus-Centered Functional Groups for Modified Oligonucleotides and Other Natural Phosphates

The Preparation of New Phosphorus-Centered Functional Groups for Modified Oligonucleotides and Other Natural Phosphates

Efforts to develop synthetic methodologies allowing the preparation of α,α– difluorophosphonothioates, α,α–difluorophosphonodithioates, α,α–difluorophosphono- trithioates, and α,α–difluorophosphinates are reviewed in the light of applications in the field...

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Bibliographic Details
Main Authors: S. Piettre, G. Gouhier, J. Valnot, S. Glatigny, S. Balieu, C. Salcedo, I. Kalinina, O. Dubert, G. Garipova, C. Lopin, A. Gautier
Format: Article
Language:English
Published: MDPI AG 2005-09-01
Series:Molecules
Subjects:
Phosphate isoster
difluorophosphonates
difluoro-H-phosphinates
nucleotide analogue
cyclitol analogue.
Online Access:http://www.mdpi.com/1420-3049/10/9/1048/

Internet

http://www.mdpi.com/1420-3049/10/9/1048/

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