ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data
Abstract Background Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process known as “imputation”, avoids apparent inf...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-3144-3 |