The well-accepted notion that gene amplification contributes to increased expression still remains, after all these years, a reasonable but unproven assumption
"Gene amplification causes overexpression" is a longstanding and well-accepted concept in cancer genetics. However, raking the whole literature, we find only statistical analyses showing a positive correlation between gene copy number and expression level, but do not find convincing experi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Carcinogenesis |
| Subjects: | |
| Online Access: | http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2016;volume=15;issue=1;spage=3;epage=3;aulast=Jia |