Macrophage: A Potential Target on Cartilage Regeneration

Macrophage: A Potential Target on Cartilage Regeneration

Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and socioeconomic burden. Synovial inflammation and articular inflammatory environment are the key factor for chondrocytes apoptosis and hypertrophy, ectopic bone formation and OA progression. To effectively treat OA, it...

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Bibliographic Details
Main Authors: Tiago Lazzaretti Fernandes, Andreas H. Gomoll, Christian Lattermann, Arnaldo Jose Hernandez, Daniela Franco Bueno, Mariane Tami Amano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
M1/M2 macrophages
cartilage regeneration
synovial inflammation
mesenchymal stem cells
osteoarthritis
articular cartilage
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00111/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00111/full

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