Epstein-Barr Virus Early Protein BFRF1 Suppresses IFN-β Activity by Inhibiting the Activation of IRF3

Epstein-Barr Virus Early Protein BFRF1 Suppresses IFN-β Activity by Inhibiting the Activation of IRF3

Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis that is closely associated with several human malignant diseases, while type I interferon (IFN-I) plays an important role against EBV infection. As we all know, EBV can encode some proteins to inhibit the production of IFN-I...

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Bibliographic Details
Main Authors: Ping Wang, Yangxi Deng, Yingjie Guo, Zuo Xu, Yiwen Li, Xiaowen Ou, Li Xie, Manjiao Lu, Jiayi Zhong, Bolin Li, Li Hu, Shenyu Deng, Tao Peng, Mingsheng Cai, Meili Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
innate immunity
EBV BFRF1
IRF3
IFN-β
ISG54
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.513383/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.513383/full

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