Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

<p>Abstract</p> <p>Background</p> <p>Epistasis is recognized as a fundamental part of the genetic architecture of individuals. Several computational approaches have been developed to model gene-gene interactions in case-control studies, however, none of them is suitable...

Full description

Bibliographic Details
Main Authors: Beretta Lorenzo, Santaniello Alessandro, van Riel Piet LCM, Coenen Marieke JH, Scorza Raffaella
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/416