Impact of lifestyle Intervention on branched‐chain amino acid catabolism and insulin sensitivity in adolescents with obesity

Introduction Insulin resistance in adolescents with obesity associates with a sex‐dependent metabolic ‘signature’ comprising branched‐chain amino acids (BCAAs), glutamate and C3/C5 acylcarnitines (C3/C5), implicating altered flux through BCAA catabolic pathways. Here, we investigated the effects of...

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Bibliographic Details
Main Authors: Catherine Jachthuber Trub, Metin Balikcioglu, Michael Freemark, James Bain, Michael Muehlbauer, Olga Ilkayeva, Phillip J. White, Sarah Armstrong, Truls Østbye, Steven Grambow, Pinar Gumus Balikcioglu
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Endocrinology, Diabetes & Metabolism
Subjects:
Online Access:https://doi.org/10.1002/edm2.250