Microscopic Photosensitization: A New Tool to Investigate the Role of Mitochondria in Cell Death

Active involvement of mitochondria in cell death has been well-documented, but local apoptotic signaling between subsets of mitochondria has been poorly explored to date. Using mitochondrially localized CMXRos as a photosensitizer coupled to laser irradiation by confocal laser scanning microscopy, w...

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Bibliographic Details
Main Authors: May-Ghee Lum, Tetsuhiro Minamikawa, Phillip Nagley
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2002.227