The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS

Objective(s): Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A. Rich fruits on some apoptotic and autophagy genes in human gastric cancer cell line AGS. Materials and Methods: Using quantitative...

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Bibliographic Details
Main Authors: Naser Jafargholizadeh, Seyed Jalal Zargar, Younes Aftabi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_10193_dd7b3d5dede0a21dadcc20b9dd478645.pdf